Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy
Gene transfer of drug resistance (CTX-R) genes can be used to protect the hematopoietic system from the toxicity of anticancer chemotherapy and this concept recently has been proven by overexpression of a mutant O6-methylguaninemethyltransferase in the read more hematopoietic system of glioblastoma patients treated with temozolomide.Given its prote